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  • Differentiation therapy of myelodysplastic syndromes with retinoic acid. ///R.Ohno. /// Leukemia & Lymphoma 14:401-409,1994
  • All-trans retinoic acid therapy in relapsed/refractory or newly diagnosed acute promyelocytic leukemia(APL) in Jfpan. /// R.Ohno, K.Ohnishi, A.Takeshita, M.Tanimoto, H.Murakami, A.Kanamaru, N.Asou, T.Kobayashi, K.Kuriyama, E.Ohmoto,x .Sakamaki, K.Tsubaki, A.Hiraoka, O.Yamada, HOh, S.Furusawa, S.Matsuda and T.Naoe. /// Leukemia 8(suppl.3):S64-S69,1994
  • G-CSF in the treatment of acute myeloid leukemia:is it safe? /// R.Ohno. /// Leukemia and Lymphoma 11(Suppl.2):15-19.1994
  • All-trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia. /// A.Kanamaru, Y.Takemoto, M.Tanimoto, H.Murakami, N.Asou, T.Kobayashi, K.Kuriyama, E.Ohmoto, H.Sakamaki, K.Tsubaki, A.Hiraoka, O.Yamada, H.Oh, K.Saito, S.Matsuda, K.Minato, T.Ueda, R.Ohno and the Japan Adult Leukemia Study Group (JALSG). /// Blood 85:1202-1206,1995
  • Prognostic significance of the RT-PCR assay of PML-RARA transcripts in acute promyelocytic leukemia. ///H.Fukutani, T.Naoe, R.Ohno , H.Yoshida, H.Kiyoi, S.Miyawaki, H.Morishita, F.Sano, H.Kamibayashi, K.Matsue, T.Miyake, S.Hasegawa, Y.Ueda, T.Kato, H.Kobayashi, C.Shimazaki, M.Kobayashi, R.Kurane, H.Sakota, K.Masaki, T.Wakayama, K.Tohyama, Y.Nonaka, H.Natori and the leukemia Study Group of the Ministry of Health and Welfare (Kouseisho). ///Leukemia9:588-593,1995
  • All-trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia. /// A.Kanamaru and R.Ohno. /// Blood 86:1645,1995
  • A randomized trial comparing interferon-alpha with busulfan for newly diagnosed chronic myelogenous leukemia in chronic phase. /// K.Ohnishi, R.Ohno, M.Tomonaga, N.Kamada, K.Onozawa, A.Kuramoto, H.Dohy, H.Mizoguchi, S.Miyawaki, K.Tsubaki, Y.Miura, M.Omine, T.Kobayashi, T.Naoe, T.Ohshima, K.Hirashima, S.Ohtake, I,Takahashi, Y.Morishima, K.Naito, N.Asou, M.Tanimoto, A.Sakuma, K.Yamada and the Kouseisho Lukemia Study Group. /// Blood 86:906-916,1995
  • Isoforms of PML-retinoic acid receptor alpha fused transcripts affect neither clinical features of acute promyelocytic leukemia nor prognosis after treatment with all-trans retinoic acid. /// H.Fukutani, T.Naoe, R.Ohno, H.Yoshida, S.Miyawaki, C.Simazaki, T.Miyake, Y.Nakayama, H.Kobayashi, S.Goto, A.Takeshita, S.Kobayashi, Y.Kato, K.Shiraishi, M.Sasada, S.Ohtake, H.Murakami, M.Kobayashi, N.Endo, H.Shindo, K.Matsushita, S.Hasegawa, K.Tsuji, Y.Ueda, N.Tominaga, H.Furuya, Y.Inoue, J.Takeuchi, H.Morishita, H.Iida, and the Leukemia Study Group of the Ministry of Health and Welfare(Kohseisho). /// Leukemia9:1478-1482,1995
  • Significant reduction of medical costs by differentiation therapy with all-trans retinoic acid during remission induction of newly diagnosed patients with acute promyelocytic leukemia. /// A.Takeshita, H.Sakamaki, S.Miyawaki, T.Kobayashi, K.Kuriyama, O.Yamada, H.Oh, T.Takenaka, N.Asou, R.Ohno and the Japan Adult Leukemia Sutdy Group (JALSG). /// Cancer76:602-608,1995
  • Recent progress in the treatment of adult acute leukemia in Japan. /// R.Ohno for the Japan Adalt Leukemia Study Group (JALSG). /// Cancer Chemotherapy 10:73-79,1995
  • Randomized trials between behenoyl cytarabine and cytarabine in combination induction and consolidation therapy, and with or without ubenimex after maintenance/intensification therapy in adult acute myeloid leukemia. /// T.Kobayashi, S.Miyawaki, M.Tanimoto, K.Kuriyama, H.Murakami, M.Yoshida, S.Minami, K.Tsubaki, E.Ohmoto, H.Oh, I.Jinnai, H.Sakamaki, A.Hiraoka, A.Kanamaru, I.Takahashi, K.Saito, T.Naoe, O.Yamada, N.Asou, S.Kageyama, N.Emi, A.Matsuoka, M.Tomonaga, H.Saito, R.Ueda, and R.Ohno for the Japan Adult Leukemia Study Group(JALSG). /// Journal of Clinacal Oncology 14:204-213,1996
  • Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinoid, Am80. /// A.Takeshita, Y.Shibata, K.Shinjo, M.Yanagi, T.Tobita, K.Ohnishi, S.Miyawaki, K.Shudo and R.Ohno. /// Annals of Internal Medicine 124:893-896,1996
  • Expression of costimulatory molecules in human leukemias. /// N.Hirano, T.Takahashi, T.Takahashi, S.Ohtake, K.Hirashima, N.Emi, K.Saito, M.Hirano, K.Shinohara, M.Takeuchi, F.Taketazu, S.Tsunoda, M.Ogura, M.Omine, T.Sito, Y.Yazaki, R.Ueda, H.Hirai. /// Leukemia10:1168-76,1996
  • Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p161NK4A CDKN2, MTS2/p151NK4B, p53, and Rb genes in primary lymphoid malignancies. /// A.Hangaishi, S.Ogawa, N.Imamura, S.Miyawaki, Y.Miura, N.Uike, C.Shimazaki, N.Emi, K.Takeyama, S.Hirosawa, N.Kamada, Y.Kobayashi, Y.Takemoto, T.Kitani, K.Toyama, S.Ohtake, Y.Yazaki, R.Ueda, H.Hirai. /// Blood 87:4949-58,1996
  • Application of fluorescence in situ hybridization to detect residual leukemic cells with 9;22 and 15;17 translocations. /// K.Tanaka, M.Arif, M.Eguchi, T.S.Kumaravel, R.Ueda, R.Ohno, K.Iwato, T.Kyo, H.Dohy and N.Kamada. /// Leukemia11:436-440,1997
  • Case-control study of leukemia and diagnostic radiation exposure. /// H.Yuasa, N.Hamajima, R.Ueda, R.Ohno, N.Asou, A.Utsunomiya, M.Ogura, N.Takigawa, T.Ueda, A.Hiraoka, S.Matsuda, Y.Kuraishi, K.Nishikawa, N.Uike, A.Takeshita, Y.Takemoto, C.Shimazaki, H.Sakamaki, T.Ino, T.Matsushima, K.Kuriyama, H.Hirai, T.Naoe, K.Tsubaki, M.Takahashi, K.Takeyama, Y.Morishima, K.Itoh. /// Inter J Haematol 65:251-261,1997
  • Morpholosgical subtyping of acute myeloid leukemia with maturation (AML-M2): homogeneous pink-coloared cytoplasm of mature neutrophils is most characteristic of AML-M2 with t(8;21). /// H.Nakamura, K.Kuriyama, N.Sadamori, M.Mine, T.Itoyama, I.Sasagawa, K.Matsumoto, Y.Tsuji, N.Asou, S.I.Kageyama, H.Sakamaki, N.Emi, R.Ohno and M.Tomonaga. /// Leukemia11:651-655,1997
  • Treatment with a new synthetic retinoid, Am80,of acute promyelocytic leukemia relapsed from complete remission induced by all-trans retinoic acid. /// T.Tobita, A.Takeshita, K.Kitamura, K.Ohnishi, M.Yanagi, A.Hiraoka, T.Karasuno, M.Takeuchi, S.Miyawaki, R.Ueda, T.Naoe and R.Ohno. /// Blood90(3):967-973,1997
  • Human urinary macrophage colony-stimulating factor reduces the incidence and duration of febrile neutropenia and shortens the period required to finish three courses of intensive consolidation therapy in acute myeloid leukemia:a double-blind controlled study. /// R.Ohno, S.Miyawaki, K.Hatake, K.Kuriyama, K.Saito, A.Kanamaru, T.Kobayashi, Y.Kodera, K.Nishikawa, S.Matsuda, O.Yamada, E.Omoto, H.Takeyama, K.Tsukuda, N.Asou, M.Tanimoto, H.Shiozaki, M.Tomonaga, T.Masaoka, Y.Miura, F.Takaku, Y.Ohashi and K.Motoyoshi. /// Journal of Clinical Oncology 15(8):2954-2965,1997
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